polypropylene_plate

Solvent stable plates for covalent binding

Addressing a growing number of enquiries for reactive plates that are chemically robust, we have developed a range of reactive Polypropylene (PP) 96-well plates together with our customers. Our PP plates are designed for use in  compound libraries in drug screening as well as synthesis and covalent immobilization of (bio-)molecules.

In addition to functionalized, flat bottom PP-plates, PolyAn is now also offering a range of functionalized PCR-plates.

Key features

  • High chemical compatibility, e.g. against solvents like DMSO, DMF, methanol, acetone ...
  • Reactive polypropylene surfaces for synthesis and covalent immobilization
  • Minimal leaching due to covalent immobilization
  • Minimal unspecific binding due to 3D functional matrix
  • Directed (bio-orthogonal) immobilization via click-chemistry with 3D-Azide surface

Products

Id Title Packaging Volume
00 800 001 3D-Amino 96-well PP plate, flat bottom 4 Plates/Box
00 800 251 3D-Epoxy 96-well PP plate, flat bottom1 4 Plates/Box
00 800 451 3D-NHS 96-well PP plate, flat bottom2 4 Plates/Box
00 800 601 3D-Azide 96-well PP plate, flat bottom3 4 Plates/Box

1) PolyAn's 3D-Epoxy functionalized 96-well microplates are used for covalent immobilization of biomolecules. Epoxides are cyclic ethers with a highly strained three member ring. Epoxy rings can be easily reacted with nucleophiles e.g. amines, hydrazines, thiols, hydroxides and carboxyl groups

2) PolyAn's 3D-NHS functionalized 96-well microplates are used for covalent immobilization of biomolecules. The NHS-ester reacts immediately with the NH2- terminus of biochemical species to form a covalent bond with the surface

3) 3D-Azide functionalized plates for covalent coupling of Alkyne- or DBCO- modified biochemical species via click-chemistry

PolyAn also offers plates for colorimetric, chemiluminescence and fluorescent detection systems, respectively. Please go to the sections for ELISA-plates, covalently coated Streptavidin & Neutravidin plates or glass bottom plates to select from a wide range of surfaces and well designs

Customized plate surfaces

Please do not hesitate to contact us, if you require a special surface for binding of your biomolecules that is not listed in the products table. Other plate formats and substrates can be equipped with our surfaces as part of our Molecular Surface Engineering Services. We are also happy to support you in developing suitable protocols for coating on our plates