Acclaimed water hydraulic manipulator for patch clamping.

This was Narishige's first water hydraulic micromanipulator specially designed for patch clamping. Its water hydraulic system has a lower coefficient of expansion than an oil hydraulic system, and allows precise movement. A 5:1 cartridge is incorporated to minimize drifting. The large, rigid driving unit enables fine movements and coarse manipulations and a sturdy ball joint is also used. Installation is made more rigid by securing attachments with a double adaptor or an isolation table, eliminating direct attachments to the bar. The drum type control unit has a large handle for precise operation and high linear repeatability. Overall, design considerations are focused on precision movement and stability over long periods of time

* To install the manipulator on the microscope, a mounting adapter suitable for the microscope is required separately

* Alternatively, the manipulator can be mounted directly on the isolation table

* The patch clamp headstage holder AP-13-2 can be attached to the ball joint B-9 included in the manipulator

* The One-Axis Water Hydraulic Micromanipulator MHW-4 (sold separately) can be attached to the ball joint B-9 included in the manipulator, allowing for the addition of a diagonal axis to the XYZ axes

Joint

B-9	UST-1
Ball Joint (MHW-3 accessories) The dedicated ball joint included with the MHW-3 is also available for separate purchase as B-9. After attaching the ø7mm holder (H-12) or patch clamp headstage holder (AP-13-2), it can be freely rotated and adjusted to various angles.	Solid Universal Joint (sold separately) It securely holds the electrode and allows for free angle adjustment. Replacing the MHW-3 ball joint (B-9) with this improves stability. The patch clamp headstage holder AP-13-3 can be mounted.

Setting example

Installation onto the mounting adaptor (inverted microscope)	Installation onto the isolation table system

* The manipulator can be installed on the isolation table with a third-party magnetic base using mounting plate GJ-12A (sold separately)

	Please use a magnetic base that meets the following specifications: the mounting plate GJ-12A (sold separately)
Set-up of the MHW-3, GJ-12A, magnetic base, and ITS2	Accessories included in GJ-12A Mounting screw (M4×8): 4 pieces (for the magnet installation) Mounting screw (Low head M6×8): 2 pieces. Hex wrench (width across flats: 3 mm): 1 piece

Options

Patch Clamp Headstage Holders

The included ball joint B-9 can be mounted with the patch amplifier headstage holder AP-13-2. If using UST-1 instead of B-9, AP-13-3 can be mounted

AP-13-2	AP-13-3
For attaching to B-9 (Block-equipped for B-9)	For attaching either solid universal joint or various manipulators (Block-equipped type for various types)

* The holder can be selected according to each maker's model and manipulator.

One-axis Water Hydraulic Micromanipulator

By attaching the one-axis water hydraulic micromanipulator MHW-4 (precision: 0.2 µm / one rotation 50 µm) to the included ball joint B-9, four-dimensional (XYZ + diagonal) drive is possible. Alternatively, using the solid universal joint UST-1 with the separately sold P-11 enables the same four-dimensional drive

Set-up image of MHW-4 and MHW-3 (using B-9)

Accessories

NR-35	MHW-A
Rotating Adjustable Clamp Attaching it to the lower part of the MHW-3's coarse drive unit allows the entire manipulator to rotate, making electrode removal and sample replacement easier	Tilting Adaptor The adaptor attaches between the MHW-3's coarse and fine drive units, enabling tilt adjustment of the fine drive unit

Specification

System Diagram